CRP Monoclonal Antibody

Size

100ug

Clone Number

15E7B4

Aliases

CRP

Immunogen Species

Human

UniProt ID

P02741

Immunogen

Recombinant Human CRP Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

Background

"C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, the levels of which rise in response to inflammation (i.e., C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion from macrophages and T cells). Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).It is a member of the pentraxin family of proteins.It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified."

Clonality

Monoclonal

Isotype

IgG

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CRP

Research Areas

Epigenetics and Nuclear Signaling;Cardiovascular;Immunology?Metabolism