CRM1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B| MPAK| and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CRM1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

117810

synonyms

CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog