CRM1 (Acetyl Lys568) Polyclonal Antibody

Ab type

Primary antibody

Background

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

123386

synonyms

XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog