CRK Monoclonal Antibody

Size

Clone Number

Aliases

p38, CRKII

Immunogen Species

Human

UniProt ID

P46108

Immunogen

Purified recombinant human CRK protein fragments expressed in E.coli.

Raised in

Mouse

Species Reactivity

Human,Dog,Rabbit,Mouse

Tested Applications

ELISA,WB;Recommended dilution:WB:1:500-1:5000

Background

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CRK

Research Areas

Cancer;Signal transduction