Crk-L Polyclonal Antibody

Ab type

Primary antibody

Background

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Reactivity

Human;Mouse;Rat;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CrkL. AA range:173-222

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

33777

synonyms

CRKL; Crk-like protein