Crk-L(Phospho Tyr207) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CrkL around the phosphorylation site of Tyr207. AA range:173-222

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

33777

synonyms

Crk-like protein; CRKL; Crk-like protein