CREM Polyclonal Antibody

Ab type

Primary antibody

Background

CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

37006

synonyms

CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER