CPT1A Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable)| together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CPT1A

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

CPT1A; Carnitine O-palmitoyltransferase 1; liver isoform; CPT1-L; EC 2.3.1.21; Carnitine O-palmitoyltransferase I; liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A