CPN cat Polyclonal Antibody

Ab type

Primary antibody

Background

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; CPN1 encodes the catalytic subunit. Mutations in CPN1 can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

52286

synonyms

CPN1; ACBP; Carboxypeptidase N catalytic chain; CPN; Anaphylatoxin inactivator; Arginine carboxypeptidase; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; Kininase-1; Lysine carbox