ABCbiolab
SKU:ABCB01416
CPI-17 Polyclonal Antibody
CPI-17 Polyclonal Antibody
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Ab type
Primary antibody
Background
The protein encoded by PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A) belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for PPP1R14A.
Reactivity
Human;Mouse;Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human CPI17 alpha. AA range:5-54
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
16693
synonyms
PPP1R14A; CPI17; PPP1INL; Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17
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