COX6c Polyclonal Antibody

Ab type

Primary antibody

Background

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. COX6C is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human COX6C. AA range:11-60

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

8781

synonyms

COX6C; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide VIc