CORIN Antibody

Size

100ul

Clone Number

Aliases

activated protease fragment antibody; ATC 2 antibody; ATC2 antibody; Atrial natriuretic peptide-converting enzyme antibody; Atrial natriuteric peptide converting enzyme antibody; Corin antibody; Corin serine peptidase antibody; CORIN_HUMAN antibody; CRN antibody; Heart specific serine proteinase antibody; Heart specific serine proteinase ATC2 antibody; Heart-specific serine proteinase ATC2 antibody; MGC119742 antibody; Pro ANP convertase antibody; Pro ANP converting enzyme antibody; Pro-ANP-converting enzyme antibody; TMPRSS 10 antibody; TMPRSS10 antibody; Transmembrane protease serine 10 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5Q5

Immunogen

Recombinant Human Atrial natriuretic peptide-converting enzyme protein (1-110AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CORIN

Research Areas

Cardiovascular; Cell biology