COPG2 Antibody

Size

100ug

Clone Number

Aliases

2 COP antibody; Coat protein nonclathrin gamma 2 cop antibody; Coatomer protein complex subunit gamma 2 antibody; Coatomer subunit gamma 2 antibody; Coatomer subunit gamma-2 antibody; COPG 2 antibody; Copg2 antibody; COPG2_HUMAN antibody; DKFZp761N09121 antibody; FLJ11781 antibody; Gamma 2 coat protein antibody; Gamma 2 COP antibody; Gamma-2-coat protein antibody; Gamma-2-COP antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UBF2

Immunogen

Recombinant Human Coatomer subunit gamma-2 protein (676-823AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

COPG2

Research Areas

Signal transduction