COL7A1 Polyclonal Antibody

Ab type

Primary antibody

Background

COL7A1 encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

295220

synonyms

COL7A1; Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen