COL4A6 Polyclonal Antibody

Ab type

Primary antibody

Background

COL4A6 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, COL4A6 is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen IV alpha6. AA range:1201-1250

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

163807

synonyms

COL4A6; Collagen alpha-6(IV) chain