CNPase Polyclonal Antibody

Ab type

Primary antibody

Background

2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CNPase. AA range:59-108

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

47579

synonyms

CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase