CLTC Antibody, Biotin conjugated

Size

100ul

Clone Number

Aliases

Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17), CLTC, CLH17 CLTCL2 KIAA0034

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q00610

Immunogen

Recombinant Human Clathrin heavy chain 1 protein (851-990aa)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Plays a role in early autophagosome formation (PubMed:20639872).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CLTC

Research Areas

Others