CLN1 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by PPT1 (palmitoyl-protein thioesterase 1) is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in PPT1 are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for PPT1.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CLN1. AA range:16-65

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

34193

synonyms

PPT1; PPT; Palmitoyl-protein thioesterase 1; PPT-1; Palmitoyl-protein hydrolase 1