CLK1 Polyclonal Antibody

Ab type

Primary antibody

Background

CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein (CDC like kinase 1) phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for CLK1.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CLK1. AA range:101-150

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

57205

synonyms

CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1