CLK1 Antibody

Size

100ul

Clone Number

Aliases

CDC like kinase 1 antibody; CDC-like kinase 1 antibody; CDC28/CDC2 like kinase antibody; CLK antibody; CLK/STY antibody; Clk1 antibody; CLK1_HUMAN antibody; Dual specificity protein kinase CLK1 antibody; Protein tyrosine kinase STY antibody; STY antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49759

Immunogen

Recombinant Human Dual specificity protein kinase CLK1 protein (1-130AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CLK1

Research Areas

Epigenetics and Nuclear Signaling; Signal transduction