CLEC7A Antibody

Size

100ug

Clone Number

Aliases

Beta GR antibody; Beta-glucan receptor antibody; BGR antibody; C type calcium dependent carbohydrate recognition domain lectin superfamily member 12 antibody; C type lectin domain family 7 member a antibody; C-type lectin domain family 7 member A antibody; C-type lectin superfamily member 12 antibody; CANDF4 antibody; CLC7A_HUMAN antibody; CLEC7A antibody; CLEC7A protein antibody; Clecsf12 antibody; DC-associated C-type lectin 1 antibody; Dectin 1 antibody; DECTIN 1 receptor antibody; Dectin-1 antibody; Dectin1 antibody; Dendritic cell associated C type lectin 1 antibody; Dendritic cell-associated C-type lectin 1 antibody; Lectin like receptor 1 antibody; Putative transmembrane protein dectin 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BXN2

Immunogen

Recombinant Human C-type lectin domain family 7 member A protein (1-44AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CLEC7A

Research Areas

Immunology