ABCbiolab
SKU:ABCB01246
Cleaved-ITI-H1 (D672) Polyclonal Antibody
Cleaved-ITI-H1 (D672) Polyclonal Antibody
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Ab type
Primary antibody
Background
ITIH1 encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3.
Reactivity
Human;Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human ITIH1. AA range:623-672
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
101389
synonyms
ITIH1; IGHEP1; Inter-alpha-trypsin inhibitor heavy chain H1; ITI heavy chain H1; ITI-HC1; Inter-alpha-inhibitor heavy chain 1; Inter-alpha-trypsin inhibitor complex component III; Serum-derived hyalur
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