Cleaved-Cathepsin D LC (G65) Polyclonal Antibody

Ab type

Primary antibody

Background

CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Reactivity

Human;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CATD. AA range:46-95

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44552

synonyms

CTSD; CPSD; Cathepsin D