Cleaved-Cathepsin D HC (L169) Polyclonal Antibody

Ab type

Primary antibody

Background

CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CATD. AA range:150-199

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44552

synonyms

CTSD; CPSD; Cathepsin D