Cleaved-C1r HC (R463) Polyclonal Antibody

Ab type

Primary antibody

Background

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human C1R. AA range:414-463

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

80174

synonyms

C1R; Complement C1r subcomponent; Complement component 1 subcomponent r