Claudin-3(Phospho Tyr219) Polyclonal Antibody

Ab type

Primary antibody

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets| forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet| with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene| a member of the claudin family| is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin| and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 3 around the phosphorylation site of Tyr219. AA range:171-220

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

23319

synonyms

Claudin-3; CLDN3; C7orf1; CPETR2; Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Rat ventral prostate.1 protein homolog; hRVP1