Claudin-10 Polyclonal Antibody

Ab type

Primary antibody

Background

CLDN10 (claudin 10) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of CLDN10 is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

24488

synonyms

CLDN10; Claudin-10; OSP-like protein