CLASP1 Antibody

Size

100ul

Clone Number

Aliases

1700030C23Rik antibody; 5730583A19Rik antibody; B130045P17Rik antibody; CLAP1_HUMAN antibody; clasp1 antibody; CLIP associating protein 1 antibody; CLIP associating protein CLASP1 antibody; CLIP-associating protein 1 antibody; Cytoplasmic linker associated protein 1 antibody; Cytoplasmic linker-associated protein 1 antibody; DKFZp686D1968 antibody; DKFZp686H2039 antibody; FLJ33821 antibody; FLJ41222 antibody; hOrbit1 antibody; KIAA0622 antibody; MAST1 antibody; MGC131895 antibody; mKIAA0622 antibody; Multiple asters 1 antibody; Multiple asters homolog 1 antibody; Protein Orbit homolog 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7Z460

Immunogen

Recombinant Human CLIP-associating protein 1 protein (1389-1538AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CLASP1

Research Areas

Cell biology