Chymase Polyclonal Antibody

Ab type

Primary antibody

Background

CMA1 encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Chymase.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

27325

synonyms

CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I