CHRDL1 Monoclonal Antibody

Size

Clone Number

Aliases

CHL, VOPT, NRLN1, dA141H5.1

Immunogen Species

Human

UniProt ID

Q9BU40

Immunogen

Purified recombinant human CHRDL1 protein fragments expressed in E.coli.

Raised in

Mouse

Species Reactivity

Human,Rat

Tested Applications

ELISA,WB;Recommended dilution:WB:1:500-1:5000

Background

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CHRDL1

Research Areas

Neuroscience;Stem cells