Chr-A Polyclonal Antibody

Ab type

Primary antibody

Background

Chromogranin A encoded by CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. CHGA product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for CHGA.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Chr-A. AA range:311-360

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

50730

synonyms

CHGA; Chromogranin-A; CgA; Pituitary secretory protein I; SP-I