CHIA Antibody

Size

100ul

Clone Number

Aliases

Acidic mammalian chitinase [Precursor] antibody; Acidic mammalian chitinase antibody; AMCase antibody; Chia antibody; CHIA_HUMAN antibody; CHIT2 antibody; chitinase; acidic antibody; DKFZp313J1722 antibody; ECF L antibody; Lung specific protein TSA1902 antibody; Lung-specific protein TSA1902 antibody; RP5 1125M8.1 antibody; TSA1902 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BZP6

Immunogen

Recombinant Human Acidic mammalian chitinase protein (1-368AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CHIA

Research Areas

Immunology; Microbiology; Signal transduction