CHCHD3 Antibody

Size

100ul

Clone Number

Aliases

CHCH3_HUMAN antibody; CHCHD 3 antibody; Chchd3 antibody; Coiled coil helix coiled coil helix domain containing 3 antibody; Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody; FLJ20420 antibody; MINOS3 antibody; mitochondrial antibody; Mitochondrial inner membrane organizing system 3 antibody; PPP1R22 antibody; Protein phosphatase 1 regulatory subunit 22 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NX63

Immunogen

Recombinant Human MICOS complex subunit MIC19 protein (1-227AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:25781180).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CHCHD3

Research Areas

Tags & Cell Markers; Metabolism; Signal transduction