Cfb Antibody

Size

100ug

Clone Number

Aliases

Cfb antibody; Bf antibody; H2-BfComplement factor B antibody; EC 3.4.21.47 antibody; C3/C5 convertase) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment] antibody

Immunogen Species

Mus musculus (Mouse)

UniProt ID

P04186

Immunogen

Recombinant Mouse Complement factor B protein (23-761AA)

Raised in

Rabbit

Species Reactivity

Mouse, Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Cfb

Research Areas

Immunology