CEP170 Polyclonal Antibody

Ab type

Primary antibody

Background

The product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP170. AA range:701-750

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

175293

synonyms

CEP170; FAM68A; KAB; KIAA0470; Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein