CENPJ Antibody

Size

100ug

Clone Number

Aliases

BM032 antibody; CENP-J antibody; CENPJ antibody; CENPJ_HUMAN antibody; Centromere protein J antibody; Centrosomal P4.1-associated protein antibody; CPAP antibody; LAG-3-associated protein antibody; LAP antibody; LIP1 antibody; LYST interacting protein LIP1 antibody; LYST interacting protein LIP7 antibody; LYST-interacting protein 1 antibody; MCPH6 antibody; Sas 4 antibody; SASS4 antibody; SCKL4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HC77

Immunogen

Recombinant Human Centromere protein J protein (1082-1248AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500

Background

Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CENPJ

Research Areas

Epigenetics and Nuclear Signaling