CDYL Antibody

Size

100ug

Clone Number

Aliases

CDY-like antibody; CDY-like autosomal antibody; Cdyl antibody; CDYL: chromodomain protein Y-like antibody; CDYL1 antibody; CDYL1_HUMAN antibody; chromodomain protein Y chromosome-like 6 antibody; Chromodomain protein Y like antibody; Chromodomain Y-like protein antibody; DKFZP586C1622 antibody; MGC131936 antibody; OTTHUMP00000015984 antibody; OTTHUMP00000211185 antibody; OTTHUMP00000211186 antibody; OTTHUMP00000211189 antibody; testis-specific chromodomain Y-like protein antibody; Weakly similar to enoyl-CoA hydratase [H.sapiens] antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y232

Immunogen

Recombinant Human Chromodomain Y-like protein (8-260AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:200-1:3000, IHC:1:20-1:200

Background

Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDYL

Research Areas

Epigenetics and Nuclear Signaling