CDKN1C Antibody

Size

100ug

Clone Number

Aliases

Beckwith Wiedemann syndrome antibody; BWCR antibody; BWS antibody; CDKI antibody; CDKN 1C antibody; CDKN1C antibody; CDN1C_HUMAN antibody; Cyclin dependent kinase inhibitor 1C antibody; Cyclin dependent kinase inhibitor p57 antibody; Cyclin-dependent kinase inhibitor 1C antibody; Cyclin-dependent kinase inhibitor p57 antibody; KIP 2 antibody; KIP2 antibody; p57 antibody; p57 Kip 2 antibody; p57KIP2 antibody; WBS antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49918

Immunogen

Recombinant Human Cyclin-dependent kinase inhibitor 1C protein (221-310AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDKN1C

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology