CDH1 Monoclonal Antibody

Size

100ul

Clone Number

9H2D3

Aliases

Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3], CDH1, CDHE UVO

Immunogen Species

Human

UniProt ID

P12830

Immunogen

Recombinant Human Cadherin-1 protein (155-707AA)

Raised in

Mouse

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDH1

Research Areas

Cancer; Developmental biology; Signal transduction