CDH1 Monoclonal Antibody

Size

100ul

Clone Number

Aliases

Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3], CDH1, CDHE UVO

Immunogen Species

Homo sapiens (Human)

UniProt ID

P12830

Immunogen

Synthesized peptide derived from human E-Cadherin

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Clonality

Monoclonal

Isotype

IgG1, Kappa

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugate

Non-conjugated

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDH1

Research Areas

Signal Transduction