CDCA7L Antibody

Size

100ug

Clone Number

Aliases

c Myc Interacting protein JPO2 antibody; CDA7L_HUMAN antibody; Cdca7l antibody; Cell division cycle-associated 7-like protein antibody; DKFZp762L0311 antibody; HR1 antibody; JPO2 antibody; Protein JPO2 antibody; R1 antibody; RAM2 antibody; Transcription factor RAM2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96GN5

Immunogen

Recombinant Human Cell division cycle-associated 7-like protein (14-167AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDCA7L

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology