CdcA4 Polyclonal Antibody

Ab type

Primary antibody

Background

CDCA4 (cell division cycle associated 4) encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for CDCA4. Two pseudogenes have also been identified on chromosome 1.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CDCA4. AA range:121-170

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

26114

synonyms

CDCA4; HEPP; Cell division cycle-associated protein 4; Hematopoietic progenitor protein