CDC42BPB Antibody

Size

100ug

Clone Number

Aliases

CDC42 binding protein kinase beta antibody; CDC42-binding protein kinase beta antibody; CDC42BPB antibody; DMPK like beta antibody; DMPK-like beta antibody; KIAA1124 antibody; MRCK beta antibody; MRCKB_HUMAN antibody; Myotonic dystrophy kinase related CDC42 binding kinase beta antibody; Myotonic dystrophy kinase-related CDC42-binding kinase beta antibody; Myotonic dystrophy protein kinase like beta antibody; Myotonic dystrophy protein kinase-like beta antibody; Serine/threonine protein kinase MRCK beta antibody; Serine/threonine-protein kinase MRCK beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5S2

Immunogen

Recombinant Human Serine/threonine-protein kinase MRCK beta protein (1609-1711AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200

Background

Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CDC42BPB

Research Areas

Signal transduction