Cdc25A(Phospho Ser178) Polyclonal Antibody

Ab type

Primary antibody

Background

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser178. AA range:144-193

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

59087

synonyms

M-phase inducer phosphatase 1; CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A