CD59 Monoclonal Antibody

Size

100ug

Clone Number

2E11B6

Aliases

CD59 glycoprotein,HRF-20,MAC-IP,MACIF,MIRL,CD59

Immunogen Species

Human

UniProt ID

P13987

Immunogen

Recombinant CD59 Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500

Background

CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25kd. It acts as a determinant of proximal–distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

>95%,Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD59

Research Areas

Cardiovascular;Immunology;Signal transduction?Stem cells