CD4 Monoclonal Antibody,Purified

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P01730

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,FC

Background

CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages. CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD4

Research Areas

Immunology;Stem cells