CD4 Monoclonal Antibody,PE Conjugated

Size

Clone Number

Aliases

Immunogen Species

Mouse

UniProt ID

P01730

Immunogen

Recombinant Protein

Raised in

Rat

Species Reactivity

Mouse

Tested Applications

ELISA,FC

Background

The 4AM15 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor. It is a member of the lg superfamily,primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC classII and associating with the protein tyrosine kinase, lck.1. Nakamura.T. 1992.Personal communication.2. Bendelac.A.1995.Mouse NK1 T Cells.Curr.Opin.Immunol.7:367-3743. Shevach,E.M.2000.Regulatory T cells in autoimmunity.Annu.Rev.Immunol.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD4

Research Areas

Immunology;Stem cells