CD4 Monoclonal Antibody(11A1)

Ab type

Primary antibody

Background

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Reactivity

Human,Mouse,Rat

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Immunogen

Synthetic Peptide of CD4

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

51111

synonyms

CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4