CD3E Monoclonal Antibody,Purified

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P07766

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background

4AT3 reacts with CD3, a 20-26 kDa molecule, which is expressed on all mature T lymphocytes  (approximately 60-80% of normal human peripheral blood lymphocytes), NK-T cells and some thymocytes.  CD3 associated with the T-cell receptor a/b or g/d dimer also plays a role in T-cell activation and signal transduction during antigen recognition.
* CD3 mAb is used to count mature T cells in blood.1. Ledbetter, J et al. (1981) J Exp Med 153:310-323.2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.

Clonality

Monoclonal

Isotype

IgG2a

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD3E

Research Areas

Immunology;Stem cells