CD34 Monoclonal Antibody,PE Conjugated

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P28906

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background

D34 reacts with CD34 molecule, a 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 43A1 belongs to the class II epitope. * CD34 mAb is useful for detection and saparation of hematopoietic stem cells.1. Schlossman, SL et al., eds. (1995) Leucocyte Typing V : White Cell Differentiation Antigens, Oxford University Press, New York.2. Freeman SD et al., (1995) Blood 85:20053. Thomas R and Lipsky PE. (1994) J Immunol 153:40164. Nakamura Y. et al., (1994) Blood 83:1442

Clonality

Monoclonal

Isotype

IgG3

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CD34

Research Areas

Neuroscience?Cancer?Cardiovascular;Developmental biology;Immunology;Stem cells